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Table 3 Charateristics of Patients in the Korean Cohort (n = 61)

From: Single-cell RNA sequencing identifies molecular biomarkers predicting late progression to CDK4/6 inhibition in patients with HR+/HER2- metastatic breast cancer

Parameter

N (%)

Mean age (range), y

48 (30.7–65.9)

CDK4/6i course

 Palbociclib

61 (100%)

 Abemaciclib

0

 Ribociclib

0

Endocrine therapy course

 

 Aromatase inhibitor

44 (72.1%)

 Fulvestrant

6 (9.8%)

 Others

11 (18.1%)

Mean duration of CDK4/6i + ET treatment, month (range), m

13.2 (0.7–39.8)

Form of biopsy specimens

 Fresh tissue

25 (41.0%)

 FFPE

36 (59.0%)

Prior treatment

De novo

22 (36.1%)

 Neo/Adjuvant chemotherapy

39 (63.9%)

Source of Biopsy

 Breast

38 (59.0%)

 Liver

6 (9.8%)

 Bone

4 (6.6%)

 Lung

3 (4.9%)

 Others

12 (19.7%)